Method for the preparation of high-purity pharmaceutical intermediates

The present invention is related to intermediates useful in the preparation of pharmceutically acceptable salts of (+)-7-[4-(4- fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)- pyrimidin-5-yl]-(3R,5S)-dihydroxy-hept-6-enoic acid and polymorphs of said intermediates, methods for preparatio...

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Bibliographic Details
Main Authors BARTHA FERENC LORANT, RUZSICS GYOERGY, VOLK BALAZS, BAGYINSZKI GABOR, IMRE JANOS, KOVANYINE LAX GYOERGYI, NAGY KALMAN, SIPOS EVA, BARKOCZY JOZSEF, KESZTHELYI ADRIENN, KRASZNAI GYOERGY, SIMIG GYULA, MOROVJAN GYOERGY
Format Patent
LanguageChinese
English
Published 11.09.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention is related to intermediates useful in the preparation of pharmceutically acceptable salts of (+)-7-[4-(4- fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)- pyrimidin-5-yl]-(3R,5S)-dihydroxy-hept-6-enoic acid and polymorphs of said intermediates, methods for preparation thereof and use thereof.
Bibliography:Application Number: CN201180057229