Magnetic nanometer gene vector system as well as preparation method and application thereof
The invention discloses a magnetic nanometer gene vector system as well as a preparation method and an application thereof. The gene vector system comprises electronegative magnetic nanoparticles, positive-ion vectors and genes, wherein the three components are prepared into the magnetic nanometer g...
Saved in:
Main Authors | , , , , , , , |
---|---|
Format | Patent |
Language | Chinese English |
Published |
21.08.2013
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The invention discloses a magnetic nanometer gene vector system as well as a preparation method and an application thereof. The gene vector system comprises electronegative magnetic nanoparticles, positive-ion vectors and genes, wherein the three components are prepared into the magnetic nanometer gene vector system according to certain proportions and composite sequences through electrostatic interactions. The magnetic nanometer gene vector system disclosed by the invention is simple in preparation method and has physicochemical properties of small grain diameter and proper surface charge. Compared with non-magnetic nanometer composites, the magnetic nanometer gene vector system has the advantages that the transfection efficiency to cells of the system is remarkably improved under the action of an additional magnetic field; and meanwhile, the cytotoxicity of the system is further reduced. |
---|---|
Bibliography: | Application Number: CN20131184988 |