New synthesis method of cinnarizine

The invention provides a new synthesis method of cinnarizine. The method consists of four steps. The method monitors the reaction process through GC and TLC, so that the cinnarizine yield is greatly enhanced up to over 85%. At the same time, the purity of the product of each reaction step is also hi...

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Bibliographic Details
Main Authors LI XIANHUAN, GUAN JIANTONG, WANG JIANJUN, JIANG XIAOMAN, XIAO HONG
Format Patent
LanguageChinese
English
Published 21.08.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention provides a new synthesis method of cinnarizine. The method consists of four steps. The method monitors the reaction process through GC and TLC, so that the cinnarizine yield is greatly enhanced up to over 85%. At the same time, the purity of the product of each reaction step is also high.
Bibliography:Application Number: CN20131113006