Preparation method of octyl-beta-D-glucopyranoside

• Main Authors: SUO CHENSU, MENG QINGWEN, SUN FANGGANG, GU ZHENLEI
• Format: Patent
• Language: Chinese; English
• Published: 19.06.2013
• Subjects: CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; DERIVATIVES THEREOF; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; SUGARS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

The invention provides a preparation method of octyl-beta-D-glucopyranoside. The method comprises the following steps of: mixing 2,3,4,6-tetra-acetyl bromo-glucose, octanol and zinc oxide, and reacting to obtain 1-octyl-2,3,4,6-tetra-acetyl-beta-D-glucopyranoside; and performing deacetylation protecting group reaction to obtain octyl-beta-D-glucopyranoside. Compared with an existing method of adopting silver carbonate kieselguhr as a catalyst, the method provided by the invention adopts zinc oxide as a catalyst to prepare octyl-beta-D-glucopyranoside, and has the advantages that the zinc oxide is cheap, and the production cost of the octyl-beta-D-glucopyranoside can be lowered; and moreover, the zinc oxide is stable and easily available, and thus the preparation method is easy to operate.