Nucleic acid vaccine, immunoadjuvant of nucleic acid vaccine, and preparation methods of nucleic acid vaccine and immunoadjuvan

The invention discloses an immunoadjuvant of genetic nucleic acid vaccine pcDNA-ORF5 of porcine reproductive and respiratory syndrome viruses ORF5. The immunoadjuvant comprises eukaryotic expression plasmids pcDNA-IL-2 and pcDNA-IL-4. The eukaryotic expression plastids pcDNA-IL-2 and pcDNA-IL-4 cons...

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Bibliographic Details
Main Authors TANG DEYUAN, ZENG ZHIYONG, MA PING, TAO YUSHUN, LIU XIA, LI CHUNYAN, WANG BIN
Format Patent
LanguageChinese
English
Published 10.04.2013
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention discloses an immunoadjuvant of genetic nucleic acid vaccine pcDNA-ORF5 of porcine reproductive and respiratory syndrome viruses ORF5. The immunoadjuvant comprises eukaryotic expression plasmids pcDNA-IL-2 and pcDNA-IL-4. The eukaryotic expression plastids pcDNA-IL-2 and pcDNA-IL-4 constructed by cytokines IL-2 and IL-4 are used together as the immunoadjuvant of the porcine reproductive and respiratory syndrome viruses, and the immunoadjuvant can obviously improve the immune effect of the vaccine.
Bibliography:Application Number: CN20121583983