Conjugates for the prevention or treatment of nicotine addiction

The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment...

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Main Authors MEHELIC PAUL ROBERT, STEAD DAVID R, DAVIS HEATHER LYNN, THORN JENNIFER MARIE, PARSONS ERIN KRISTEN, GERVAIS DAVID P, KOLHE PARAG ASHOK, BROWN ALAN DANIEL, BHATTACHARYA KESHAB, ANASTASIOU NICKOLAS, FINNEMAN JARI ILMARI, MERSON JAMES R, JONES LYN HOWARD, MCCLUSKIE MICHAEL J, PRYDE DAVID CAMERON
Format Patent
LanguageEnglish
Published 10.06.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.
Bibliography:Application Number: CN201180027358