Method for preparing high molecular weight poly(L-lactide-co-caprolactone) random copolymer

• Main Authors: RUAN JIANMING, SHEN XIONGJUN
• Format: Patent
• Language: Chinese; English
• Published: 06.02.2013
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP

The invention discloses a method for preparing a high molecular weight poly(L-lactide-co-caprolactone) random copolymer. The method comprises the following steps of: preparing high-purity L-lactide(L-LA); and performing ring opening copolymerization on L-lactide and purified epsilon-caprolactone in the presence of a proper amount of stannous octoate to polymerize for a certain time under a certain temperature, so as to prepare the high molecular weight poly(L-lactide-co-caprolactone) random copolymer. The method is characterized by comprising the following steps of: washing and purifying the manufactured coarse L-LA once, purifying the coarse L-LA for two to three times by using ethyl acetate or acetone, and drying under specific conditions and time; purifying the epsilon-caprolactone before use; and proportioning the high-purity L-lactide and the purified epsilon-caprolactone according to the needs, adding a proper amount of stannous octoate catalyst solution, and polymerizing a certain time under certain co