Method for producing induced pluripotent stem cells

Provided is a method for producing induced pluripotent stem cells that have a low potential for tumor formation and ensure a high induction efficiency. The method for producing induced pluripotent stem cells includes a step for introducing nucleic acid which accelerates expression of at least one ge...

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Main Authors ISHII HIDESHI, TANEMURA MASAHIRO, MORI MASAKI, MIYAZAKI SUSUMU, HARAGUCHI NAOTSUGU, HOSHINO HIROMITSU, OMURA YOSHIAKI, MIYOSHI NORIKATSU, DOKI YUICHIRO, NAGAI KENICHI
Format Patent
LanguageChinese
English
Published 16.01.2013
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:Provided is a method for producing induced pluripotent stem cells that have a low potential for tumor formation and ensure a high induction efficiency. The method for producing induced pluripotent stem cells includes a step for introducing nucleic acid which accelerates expression of at least one gene selected from the group consisting of NANOG gene, SOX2 gene, OCT3/4 gene, KLF4 gene, LIN28 gene and c-MYC gene in somatic cells.
Bibliography:Application Number: CN2011819591