Process for the preparation of gadobenate dimeglumine complex in a solid form

The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly a...

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Main Authors FERRIGATO AURELIA, LATTUADA LUCIANO, MOROSINI PIER FRANCESCO, UGGERI FULVIO, CERAGIOLI SILVIA, FRETTA ROBERTA, ANELLI PIER LUCIO
Format Patent
LanguageChinese
English
Published 10.10.2012
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly advantageous for the industrial scale as the solid form may be obtained by employing water as a solvent, which is a non-toxic solvent, easy to handle and basically not requiring troublesome health or safety precautions.
Bibliography:Application Number: CN201080059517