Green preparation method of curcumin under catalysis effect of sulfonic acid functionalization ionic liquid

• Main Authors: HOU XIULIANG, GAO LIHONG, YUAN SHUNFU, GAO HAIYAN, HUANG JIEFANG, WANG HAIJUN, YUE JUAN, CAI LI
• Format: Patent
• Language: Chinese; English
• Published: 03.10.2012
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention discloses a green method for synthesizing curcumin through sulfonic acid functionalization ionic liquid catalysis. The method comprises the steps that boric anhydride is used for protecting methylene of diacetone, sulfonic acid functionalization ionic liquid is added for catalyzing the diacetone and 4-hydroxy-3-methoxybenzaldehyde to take condensation reaction, then, dilute acetic acid solution is added for carrying out decomposition, and in addition, the post treatment is carried out. Sulfonic acid functionalization ionic liquid catalysts can be repeatedly used for many times through being washed and dried. Compared with the prior art, the method has the beneficial effects that the synthesis process of the used sulfonic acid functionalization ionic liquid is simple, the conversion is complete, the yield is high, and the heat stability is good; automatic phase separation with products can be realized after reaction, and the post treatment is simple; and the ionic liquid after the condensation re