Lignan compound in magnolia as well as preparation method and application thereof

• Main Authors: LI YINKE, SHEN YANQIONG, YANG LIYING, HU QIUFEN, SU LIDAN
• Format: Patent
• Language: Chinese; English
• Published: 29.08.2012
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; IMPREGNATING OR COATING OF PAPER; METALLURGY; ORGANIC CHEMISTRY; PAPER NOT OTHERWISE PROVIDED FOR; PAPER-MAKING; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PRODUCTION OF CELLULOSE; PULP COMPOSITIONS; TEXTILES; TRAPPING; TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G

The invention belongs to the field of plant chemistry and relates to a lignan compound in magnolia as well as a preparation method and an application thereof, in particular to an 8-O-4'-new lignan compound in new magnolia as well as a preparation method and an application thereof. The compound has the following structural formula shown in the specification. The preparation method comprises the following steps of: carrying out ultrasonic extraction on 95 percent of ethanol for 3-5 times after a magnolia sample is crushed, merging extracting solution, filtering, depressurizing and concentrating into an extract; and preliminarily separating the extract by using a silica-gel column chromatography and then further separating by adopting a preparative high-performance liquid chromatography. The antibacterial activity of the compound is screened. Experimental results show that the compound shows the antibacterial effect on bacillus proteus vulgaris, escherichia coli, staphylococcus, bacillus subtilis and the like.