Zebrafish liver replication model for human HCV (hepatitis C virus) genes

The invention relates to a zebrafish liver replication model for human HCV (hepatitis C virus) genes, in particular to two zebrafish HCV sub-replicon models obtained by genetic recombination and molecular biological methods, which include a zebrafish forward HCV sub-replicon model and a zebrafish tr...

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Bibliographic Details
Main Authors ZHAO YE, ZHANG JINGPU, DING CUNBAO, JIANG JIANDONG
Format Patent
LanguageChinese
English
Published 18.07.2012
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
CARE OF BIRDS, FISHES, INSECTS
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
NEW BREEDS OF ANIMALS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
TRAPPING
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Summary:The invention relates to a zebrafish liver replication model for human HCV (hepatitis C virus) genes, in particular to two zebrafish HCV sub-replicon models obtained by genetic recombination and molecular biological methods, which include a zebrafish forward HCV sub-replicon model and a zebrafish trans HCV sub-replicon model. The zebrafish HCV sub-replicon models can be used for researching molecular mechanisms of HCV genome replication, estimating efficacy, researching therapeutic strategies and the like.
Bibliography:Application Number: CN2011101490