Dihydropteridinone derivatives, preparation method and pharmaceutical use thereof

Dihydropteridinone derivatives, preparation method and pharmaceutical use thereof are disclosed. Specifically, disclosed are new dihydropteridinone derivatives represented by general formula (I), their preparation method, pharmaceutical compositions comprising said derivatives and their use as thera...

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Bibliographic Details
Main Authors SHU SIJIE, ZHANG NONG, DONG ZHENG, LIU LUNJUN, TANG PENG CHO, ZENG XIANGQUAN
Format Patent
LanguageEnglish
Published 11.03.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Dihydropteridinone derivatives, preparation method and pharmaceutical use thereof are disclosed. Specifically, disclosed are new dihydropteridinone derivatives represented by general formula (I), their preparation method, pharmaceutical compositions comprising said derivatives and their use as therapeutical agents, especially as Plk kinase inhibitors ,wherein each substituent of the general formula (I) is defined as in the specification
Bibliography:Application Number: CN201180002067