Conjugate molecules

• Main Author: LOHSE JESPER
• Format: Patent
• Language: Chinese; English
• Published: 18.01.2012
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC MACROMOLECULAR COMPOUNDS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; THEIR PREPARATION OR CHEMICAL WORKING-UP; VINEGAR; WINE

The present invention relates to compounds which are conjugates of two or more moieties capable of serving as substrates of an enzyme with peorxidase activity and one or more labels. The conjugate molecules of the invention are useful for detection of molecular targets, e.g. biological or chemical molecules, molecular structures, etc, in samples using a host of experimental schemes for detecting and visualizing such targets, e.g. immunohistochemistry (IHC), in situ hybridization (ISH), ELlSA, Southern, Northern, and Western blotting, etc. The invention also relates to compositions comprising the conjugate molecules. The labels and moieties of peroxidase substrate are not the same chemical substances and are linked together via a linker, wherein said linker is a compound comprising at least one linear chain of at least 30 consecutively connected atoms, wherein said linear chain contain at least two branching points separated by a distance of at least 30 consecutevely connected atoms and the labels and peroxida