Production method capable of improving output of lincomycin through adding glutamine

The invention relates to a production method capable of improving the output of lincomycin through adding glutamine. The production method is characterized in that: the glutamine is added in the fermentation process; the quantity of added glutamine is 0.04-0.06% of the weight of a culture medium; an...

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Bibliographic Details
Main Authors YE RUIFANG, MAO QUANGUI, ZHANG HONGZHOU, LIU SHOUQIANG, WANG MEIZHU, QIAO XIANTING, LV HEPING
Format Patent
LanguageChinese
English
Published 23.11.2011
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to a production method capable of improving the output of lincomycin through adding glutamine. The production method is characterized in that: the glutamine is added in the fermentation process; the quantity of added glutamine is 0.04-0.06% of the weight of a culture medium; and the adding time of the glutamine is 72-96 hours. The production method has the following advantage that: the output of the lincomycin can be obviously improved through adding the glutamine which does not serve as a precursor for synthesizing the lincomycin in the fermentation process.
Bibliography:Application Number: CN20111184750