Antibodies against FcRn and use thereof

This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.

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Bibliographic Details
Main Authors LIU LIMING, TENHOOR CHRISTOPHER, LADNER ROBERT CHARLES, DUMONT JENNIFER, MURUGANANDAM ARUMUGAM, BITONTI ALAN J, STATTEL JAMES, SATO AARON, WOOD CLIVE, MCDONNELL KEVIN
Format Patent
LanguageChinese
English
Published 10.08.2011
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
Bibliography:Application Number: CN200980124409