Compounds and compositions as protein kinase inhibitors

The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kina...

Full description

Saved in:
Bibliographic Details
Main Authors MICHELLYS PIERRE-YVES, PEI WEI, MARSILJE THOMAS H, JIANG TAO, NGUYEN TRUC NGOC, GE YONGHUI, GAO ZHAOBO, WU BAOGEN, LI YUNCHENG, ZHU XUEFENG, HUANG CHEN, CHEN BEI
Format Patent
LanguageChinese
English
Published 20.07.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-1R), and/or insulin receptor (InsR) or a combination thereof.
Bibliography:Application Number: CN200980121030