Inhibitors of carbonic anhydrase IX

Novel radiopharmaceuticals that are useful in diagnostic imaging and therapeutic treatment of disease characterized by over expression of CA-IX comprise a complex that contains a sulfonamide moiety which is capable of binding the active catalytic site of CA- IX, and a radionuclide adapted for radio-...

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Bibliographic Details
Main Authors BARONE CHRIS, BABICH JOHN W, ZIMMERMAN CRAIG, JOYAL JOHN, MARESCA KEVIN P, LU GENLIANG
Format Patent
LanguageChinese
English
Published 10.12.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel radiopharmaceuticals that are useful in diagnostic imaging and therapeutic treatment of disease characterized by over expression of CA-IX comprise a complex that contains a sulfonamide moiety which is capable of binding the active catalytic site of CA- IX, and a radionuclide adapted for radio-imaging and/or radiotherapy.
Bibliography:Application Number: CN200980107793