Branching polyamino chitosan derivative and preparation method thereof

• Main Authors: LI PENGNI, LUO XIAOMIN, LAN QIAN, JIE XING, FENG JIANYAN
• Format: Patent
• Language: Chinese; English
• Published: 11.05.2011
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES THEREOF; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; THEIR PREPARATION OR CHEMICAL WORKING-UP

The invention relates to a branching polyamino chitosan derivative and a preparation method thereof. Hydrogen bond action of amino and hydroxy in chitosan molecules causes poor swelling resistance property and poor dissolubility of the chitosan, and the chitosan is only dissolved in a special organic solvent, thus the application of the chitosan is limited. The preparation method comprises the steps of: dissolving chitosan in an organic acid solution, dissolving acrylate in lower alcohol, mixing the acrylate and the lower alcohol and adding a proper of tertiary amine, stirring for reacting for a certain time, regulating the pH, evaporating for removing water, separating out solids with alcohol or acetone, leaching, washing for several times, and drying in vacuum to obtain N-carboxyethyl chitosan ester; adding the N-carboxyethyl chitosan ester and polyamine in a flask, adding the alcohol and stirring for reacting, leaching, and washing for several times to obtain first-generation branching polyamino chitosan;