Pyridazinone glucokinase activators

Provided herein are compounds of the formula (I), wherein X, Y, Q and R1 to R3 are defined in the specification, as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing...

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Main Authors SCOTT NATHAN ROBERT, TILLEY JEFFERSON WRIGHT, QIAN YIMIN, MCDERMOTT LEE APOSTLE, SARABU RAMAKANTH, HAYNES NANCY-ELLEN, KESTER ROBERT FRANCIS, BERTHEL STEVEN JOSEPH
Format Patent
LanguageChinese
English
Published 06.04.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are compounds of the formula (I), wherein X, Y, Q and R1 to R3 are defined in the specification, as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
Bibliography:Application Number: CN200980113224