Turnover membrane bioreactor for use in micro-gravity environment

• Main Authors: DENG YULIN, LI CHUN, ZHOU XIAOHONG, JIANG YUANDA, WANG CHAO, WANG LUFENG, ZHENG SEN
• Format: Patent
• Language: Chinese; English
• Published: 16.03.2011
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; SPIRITS; VINEGAR; WINE

The invention discloses a turnover membrane bioreactor for suspended biological cell multi-batch culture in a micro-gravity environment, which mainly comprises a bioreactor reactor, an air supply system, a liquid injection system, a stirring system, a circulating pump, a temperature, dissolved oxygen, pressure and pH parameter measuring control system, an exhaust system and a liquid drainage system. In the invention, the accurate quantification of the volume of injected or drained liquid is realized by controlling the working time and flow rate of a micro peristaltic pump, a porous hydrophobic breathable membrane is used to supply oxygen required by organisms for growth, the uniform distribution of the nutrients in the reactor is realized by a central stirring paddle, carbon dioxide, which is a waste gas from the growth metabolism of microbes, is exhausted under a negative pressure produced by a vacuum pump so as not to inhibit the microbes any longer, the drainage of culture waste liquid in the reactor in a