Anti-tumor composition containing four-substance decoction extract and application thereof

• Main Authors: QIAN DAWEI, TANG YUPING, DUAN JIN'AO, JIANG HAOWEN, MA HONGYUE, ZHAN ZHEN, ZHU MIN, XU HUIQIN
• Format: Patent
• Language: Chinese; English
• Published: 16.03.2011
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides an anti-tumor composition and application thereof. The composition consists of cyclophosphamide and the four-substance decoction extract, wherein the four-substance decoction extract can be a water extract, an alcohol extract, a water-extraction alcohol-precipitation extract and the like. On the basis of a large amount of experimental research, the four-substance decoction of an ancient precipitation is screened and can obviously reduce the cardiotoxicity of an anti-tumor medicine cyclophosphamide, and after the four-substance decoction and the cyclophosphamide are scientifically proportioned and combined, the cyclophosphamide has the high anti-tumor activity and the side effects such as the cardiotoxicity are obviously reduced; and after the four-substance decoction and the cyclophosphamide are combined, the anti-tumor composition has higher medicine safety than the single cyclophosphamide, is a chemical medicine and traditional Chinese medicinal compound composition with wide applicat