Bicyclic heterocyclic derivative

Disclosed is a compound represented by the formula (I) below or a pharmaceutically acceptable salt thereof, which is effective as a renin inhibitor. (I) (In the formula, R1a represents a halogen atom or the like; R1m represents a hydrogen atom or the like; G1 represents -N(R1b)- or the like; G2 repr...

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Bibliographic Details
Main Authors IKUMA YOHEI, IKEDA JUNYA, KIMURA HIDENORI, YOSHIDA KOZO, FUKUDA NOBUHISA, FUSANO AKIRA, SAWAMURA KIYOTO, NAKAI YOSHIO, SUETSUGU SATOSHI, NAKAHIRA HIROYUKI
Format Patent
LanguageChinese
English
Published 19.01.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed is a compound represented by the formula (I) below or a pharmaceutically acceptable salt thereof, which is effective as a renin inhibitor. (I) (In the formula, R1a represents a halogen atom or the like; R1m represents a hydrogen atom or the like; G1 represents -N(R1b)- or the like; G2 represents -CO- or the like; G3 represents -C(R1c)(R1d)- or the like; G4 represents an oxygen atom or the like; R1b represents an optionally substituted C1-6 alkyl group or the like; R1c and R1d may be the same as or different from each other and independently represent a hydrogen atom or the like; R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group or the like; R3a, R3b, R3c and R3d may be the same as or different from each other and independently represent a group -A-B (wherein A represents a single bond or the like and B represents a hydrogen atom or the like); and n represents 1 or the like).
Bibliography:Application Number: CN200880127476