Preparation method of D-ribose

The invention discloses a preparation method of D-ribose. In the preparation method, a super-strong solid acid catalyst is selected, and then nucleoside is hydrolyzed into the D-ribose and purine under the catalysis of the super-strong solid acid, wherein the D-ribose has a molecular formula of C4H9...

Full description

Saved in:
Bibliographic Details
Main Authors OU RENSHU, LIN XIAO, WANG HAIBO, WANG XIAOMING, HUANG GUIJI, REN HONGFA
Format Patent
LanguageChinese
English
Published 28.11.2012
Subjects
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SUGARS
THEIR RELEVANT APPARATUS
TRANSPORTING
Online AccessGet full text

Cover

More Information
Summary:The invention discloses a preparation method of D-ribose. In the preparation method, a super-strong solid acid catalyst is selected, and then nucleoside is hydrolyzed into the D-ribose and purine under the catalysis of the super-strong solid acid, wherein the D-ribose has a molecular formula of C4H9O4CHO, and the English name of the D-ribose is ribose; the molecule structural formula of the super-strong solid acid is as follows: S2O82/TiO2; and the weight ratio of the super-strong solid acid to the nucleoside is 1-5:100. The hydrolysis reaction of the invention has the yield up to 98%-100%, and the method has less side reactions, less by-products and is easy to realize purification, thereby producing the D-ribose with high purity and high yield. The impurities are easy to be removed in the process of purifying the D-ribose, and the post-treatment difficulty is reduced.
Bibliography:Application Number: CN20101268899