Phenyl acetamide derivative

Disclosed is a compound which is useful as a GK-activator. Intensive studies are made on phenyl acetamide derivatives. As a result, it is confirmed that a phenyl acetamide derivative having a sulfonyl group and a cycloalkyl group on a phenyl group therein and a heteroaryl group on a nitrogen atom in...

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Main Authors HAYAKAWA MASAHIKO, AMINO NOBUAKI, KIDO YOSHIYUKI, NIGAWARA TAKAHIRO, OKUMURA MITSUAKI, MAKI KEISUKE, KANAI AKIRA
Format Patent
LanguageChinese
English
Published 15.12.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed is a compound which is useful as a GK-activator. Intensive studies are made on phenyl acetamide derivatives. As a result, it is confirmed that a phenyl acetamide derivative having a sulfonyl group and a cycloalkyl group on a phenyl group therein and a heteroaryl group on a nitrogen atom in an amide therein has a good GK-activating activity. The compound is useful as a therapeutic agent for diabetes, particularly type-2 diabetes, since the compound has a good GK-activating activity.
Bibliography:Application Number: CN200980102515