Process to prepare treprostinil, the active ingredient in Remodulin

This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

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Bibliographic Details
Main Authors WALSH DAVID A, PENMASTA RAJU, BATRA HITESH, TULADHAR SUDERSAN M
Format Patent
LanguageChinese
English
Published 01.12.2010
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
Bibliography:Application Number: CN200880121181