Process for the preparation of betaines

Betaines of formula R3N+-Q-COO- (I), wherein R is C1-4 alkyl and Q is C1-4 alkanediyl, optionally substituted with hydroxy, are prepared in one step by adding an Omega-halocarboxylate of formula X-Q-COOR' (II), wherein Q is as defined above, R' is C11-4 alkyl and X is chlorine, bromine or...

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Bibliographic Details
Main Authors BICKER MARKUS, PARADIES GESA, VEGHINI DARIO, ZENKLUSEN ANTON
Format Patent
LanguageChinese
English
Published 13.10.2010
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:Betaines of formula R3N+-Q-COO- (I), wherein R is C1-4 alkyl and Q is C1-4 alkanediyl, optionally substituted with hydroxy, are prepared in one step by adding an Omega-halocarboxylate of formula X-Q-COOR' (II), wherein Q is as defined above, R' is C11-4 alkyl and X is chlorine, bromine or iodine, to an aqueous solution containing a tertiary amine of formula R3N (III), Wherein R is as defined above and a base selected from alkali hydroxides and alkaline earth hydroxides. The process is particularly suited to the production of L-carnitine.
Bibliography:Application Number: CN200880117375