Alkyl galactoside receptor, preparation method and application thereof

The invention discloses an alkyl 2,3,4,6-tetra-O-acetyl-beta-D-pyran galactosyl-(1->4)-2,3-di-O-acetyl-beta-D-pyran heteroside and a preparation method thereof. The raw material lactose is completely acetylized to react with alcohol to obtain alkyl-O-hepta-acetyl galactoside, and 6-acetyl on gluc...

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Bibliographic Details
Main Authors WANG MIN, HENG LINSEN
Format Patent
LanguageChinese
English
Published 16.11.2011
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:The invention discloses an alkyl 2,3,4,6-tetra-O-acetyl-beta-D-pyran galactosyl-(1->4)-2,3-di-O-acetyl-beta-D-pyran heteroside and a preparation method thereof. The raw material lactose is completely acetylized to react with alcohol to obtain alkyl-O-hepta-acetyl galactoside, and 6-acetyl on glucose group is selectively deacetylated to obtain the target compound. The synthesizing method provided in the invention has the advantages of simple, convenient and fast operation, low cost and the like. The invention also discloses an application of alkyl galactoside receptor in fast synthesizing non-natural oligosaccharide having antitumor activity.
Bibliography:Application Number: CN20091104237