Novel amide derivative for inhibiting the growth of cancer cells

The present invention provides an amide derivative and a pharmaceutically acceptable salt thereof which selectively and effectively inhibits the growth of cancer cells induced by the overexpression of an epidermal growth factor receptor and also prevents the development of drug resistance caused by...

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Bibliographic Details
Main Authors CHAE YUN JUNG, CHA MI YOUNG, PARK BUM WOO, JUNG YOUNG HEE, CHOI BO IM, KIM HAN KYONG, BANG KEUKCHAN, AHN YOUNG-GIL, LEE GWAN SUN, KIM MAENG SUP, KIM MI RA, LEE CHANG GON, KIM SE YOUNG, LEE KWANG-OK, KO MI YOUNG
Format Patent
LanguageChinese
English
Published 24.03.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention provides an amide derivative and a pharmaceutically acceptable salt thereof which selectively and effectively inhibits the growth of cancer cells induced by the overexpression of an epidermal growth factor receptor and also prevents the development of drug resistance caused by the mutation of EGFR tyrosine kinase, and a pharmaceutical composition comprising same as an active ingredient.
Bibliography:Application Number: CN200880018825