Novel lysyl oxidases

The present invention relates to an isolated lysyl oxidase which is able to catalyze the oxidative deamination of lysyl groups in proteins or peptides to the corresponding aldehydes, with the subsequent reduction of O2 to H2O2 whereby the lysyl oxidase (a) shows a ratio of between lysyl oxidase acti...

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Bibliographic Details
Main Authors DIJK VAN ALBERTUS ALARD, BAKHUIS JANNA GARDINA, WESTERLAKEN ILJA, DEKKER PETRUS JACOBUS THEODORU
Format Patent
LanguageChinese
English
Published 17.02.2010
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to an isolated lysyl oxidase which is able to catalyze the oxidative deamination of lysyl groups in proteins or peptides to the corresponding aldehydes, with the subsequent reduction of O2 to H2O2 whereby the lysyl oxidase (a) shows a ratio of between lysyl oxidase activity for Ac-Gly-Lys-OMe and lysyl oxidase activity for benzylamine of at least 1.1, preferably at least 1.3, more preferably of at least 1.4 whereby the activities are determined at 37 degrees Celsius and an pH of 7.0; and. (b) has an optimum activity at a temperature of between 0 and 60 degrees Celcius.
Bibliography:Application Number: CN2008809278