Drug for preventing and curing H1N1 flu virus by adopting 4 (3H) quinazolone

• Main Authors: LIANG JIANPING, SHANG RUOFENG, GUO ZHITING, XU TAO, GUO YANSHENG, HUA LANYING, WANG SHUYANG, PU XIUYING, LIU YU, WANG XUEHONG, GUO WENZHU
• Format: Patent
• Language: Chinese; English
• Published: 14.10.2009
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses a drug for preventing and curing H1N1 flu virus by adopting 4 (3H) quinazolone, which relates to the field of drugs for preventing and curing flu, the chemical synthetic drugs for resisting flue virus which are more ideal at present have low selectivity, large adverse reaction and high price and are easy to generate drug resistance after long-term use. The drug adopts monomeric compound 4 (3H) quinazolone extracted from dyers woad leaves; animal experiments, in vitro experiments and clinical experiments show that the drug has good effect of resisting flu virus, wide adaptability, rich drug sources, low cost and low toxic side effects and is not easy to generate drug resistance; the produced dosage forms are tablets, oral liquid and granular formulation; the clinical application dosage of the adult body is 60mg/60Kg, and the drug is taken for 2-3 times everyday and continuously taken for 5 days.