Triazole derivatives as kinase inhibitors

The invention relates to compounds of formula (I) wherein X and R 1 to R 5 have the meaning as cited in the description and the claims. Said compounds are useful as Itk protein kinase inhibitors for the treatment or prophylaxis of immunological, inflammatory or allergic disorders. The invention also...

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Main Authors WILSON FRANCIS, TAYLOR JESS, SUNOSE MIHIRO, CANSFIELD ANDREW, RAMSDEN NIGEL, BURCKHARDT SVENJA, MIDDLEMISS DAVID, BELL KATHRYN
Format Patent
LanguageChinese
English
Published 30.10.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to compounds of formula (I) wherein X and R 1 to R 5 have the meaning as cited in the description and the claims. Said compounds are useful as Itk protein kinase inhibitors for the treatment or prophylaxis of immunological, inflammatory or allergic disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the production of and use as medicaments.
Bibliography:Application Number: CN200780037450