Method for synthesis of mixed dibasic acid dimethyl ester with sodium bisulfate catalysis

• Main Authors: XU DAN, DONG XUELIANG, ZHU JING, ZHAO XIANZENG, LI TIANXIAN, ZHANG WENNAN, WANG DONGMEI
• Format: Patent
• Language: Chinese; English
• Published: 25.05.2011
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE; THEIR RELEVANT APPARATUS; TRANSPORTING

The invention discloses a method for synthesizing mixed dibasic acid dimethyl ester by sodium bisulfate catalysis, and belongs to the field of organic chemistry synthesis. The method comprises the following steps: using sodium bisulfate as a catalyst, using mixed dibasic acid and methanol as raw materials, adding the methanol thrice to carry out esterification reaction, and obtaining the mixed dibasic acid dimethyl ester. The catalyst can be recycled, and the synthetic yield of the mixed dibasic acid dimethyl ester after being treated is more than 99 percent. The method has the advantages of high yield of the mixed dibasic acid dimethyl ester, quick reaction rate, low cost, easy separation for products, no waste discharge in production process, and the like, and solves the problem of highcost of the catalyst in the prior art, low yield of dimethyl ester, serious equipment corrosion, and the like. The method is widely applied to the chemical engineering industry, and in particular suitable for recycling the mi