Human hypoxia inducible factor-1 alpha recombinant adenovirus carrier and uses thereof

The invention relates to a mutant hypoxia inducible factor 1alpha, coded nucleic acid of the mutant hypoxia inducible factor 1alpha, a carrier containing wild coded nucleic acid of the mutant hypoxia inducible factor 1alpha, in particular to a recombinant adenovirus carrier and a drug composition co...

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Bibliographic Details
Main Authors LIU CHENG, CHEN WEI, XIE YIJUN, WU PINGSHENG, WANG YUEGANG, GUO SHOUGUI, TONG KAI, HU YINGFANG, FU RUIBIN, LAI YANXIAN
Format Patent
LanguageChinese
English
Published 19.11.2008
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to a mutant hypoxia inducible factor 1alpha, coded nucleic acid of the mutant hypoxia inducible factor 1alpha, a carrier containing wild coded nucleic acid of the mutant hypoxia inducible factor 1alpha, in particular to a recombinant adenovirus carrier and a drug composition containing the mutant hypoxia inducible factor 1 alpha, the coded nucleic acid and the carriers. The mutant protein, the nucleic acid, the carriers and the drug composition can be used to treat ischemic diseases, such as coronary heart disease, peripheral arterial ischemic vascular diseases, intermittent claudication and so on.
Bibliography:Application Number: CN20071164320