Anti-malarial compound isolated from gomphostema niveum

The present invention provides a novel antimalarial compound 3-[2-(2-Hydroxymethyl-1, 4a, 5-trimethyl-7-oxo-l, 2, 3, 4, 4a, 78, 8a-octahydronaphthalen-l-yl)-ethyl]-5H-furan-2-one of the formula (I) given below or pharmaceutically acceptable derivatives thereof, isolated from Gomphostema niveum and a...

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Main Authors NIVSARKAR MANISHA, SEKHAR KRISHNAMURTHY, KAUSHIK MAHABIR PRASHAD, PRASANNA SUBRAMANIAM, ACHARYA BADRI NARAYAN, THAVASELVAM DURAIPANDIAN
Format Patent
LanguageChinese
English
Published 08.10.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a novel antimalarial compound 3-[2-(2-Hydroxymethyl-1, 4a, 5-trimethyl-7-oxo-l, 2, 3, 4, 4a, 78, 8a-octahydronaphthalen-l-yl)-ethyl]-5H-furan-2-one of the formula (I) given below or pharmaceutically acceptable derivatives thereof, isolated from Gomphostema niveum and also provides a method for the extraction thereof as well as methods for the treatment of malaria using the compound.
Bibliography:Application Number: CN200680036982