Solid pharmaceutical composition comprising valsartan

This invention relates to a solid pharmaceutical composition containing valsartan particles characterized in that the D 50 of said valsartan particles is 150 µm or below and that the valsartan particles have a maximum diameter of no more than 1100 µm, as determined by electron microscopy, and that i...

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Bibliographic Details
Main Authors CERNOSA LIDIJA, ZUPANCIC SILVO, RANGUS MARIJA, BEVEC FRANCI, VRBINC MIHA, SLANCVOVK JANIKA
Format Patent
LanguageChinese
English
Published 30.01.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention relates to a solid pharmaceutical composition containing valsartan particles characterized in that the D 50 of said valsartan particles is 150 µm or below and that the valsartan particles have a maximum diameter of no more than 1100 µm, as determined by electron microscopy, and that it comprises 30-70 wt.-% of valsartan, 10-70 wt.-% of a diluent, 1-20 wt.-% of a disintegrant, 1-20 wt.-% of a binder and 1-10% of a lubricant, wherein the disintegrant is carboxymethylcellulose sodium.
Bibliography:Application Number: CN200580044785