Heptapeptide prepared from thymopentin and pidotimod, and synthetic method

The invention relates to seven-peptide produced with thymus gland five- peptide and pidotimod and the synthesizing method, beloning to chemical medicine production area. The method is to empoly solid synthesing method and connects five- peptide and pidotimod through amido bond. The invention is char...

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Bibliographic Details
Main Authors LIU ZHONGHUI, LIANG YONGTAO, YAN XIANGQIAN, WANG ENSI, WANG MINGZHE, LIANG TIE
Format Patent
LanguageChinese
English
Published 12.12.2007
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The invention relates to seven-peptide produced with thymus gland five- peptide and pidotimod and the synthesizing method, beloning to chemical medicine production area. The method is to empoly solid synthesing method and connects five- peptide and pidotimod through amido bond. The invention is characterized in that the pidotimod is an artificially- synthesized high- purity dipeptide, which can promote non-specific immune response and specific reaction and is polyphase broad-spectrum immunologic enhancement agent, the new compound is synthesized through connection of carboxyl of pidotimod and amidol of arginine, the metabolic process of thymus gland five- peptide begins from amidol of arginine, so it protects amidol after connection withpidotimod, and changes traditional medicine type of thymus gland five- peptide, so the clinical value is great.
Bibliography:Application Number: CN2007155615