P53 negative controllable molecule and genes encoding same

The invention discloses a p53 negative regulating and controlling molecule and encode gene, which is characterized by the following: 1) SEQ ID of sequence table is No: 1; 2) the SEQ ID No.:1 amino acid residue sequence of sequence table is replaced, missed and added by one to ten amino acid residues...

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Bibliographic Details
Main Authors YUAN YANZHI, ZHANG LINGQIANG, YIN XIUSHAN, XING GUICHUN, TIAN CHUNYAN, LI BIN, HE FUCHU, NIE JING
Format Patent
LanguageChinese
English
Published 27.08.2008
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention discloses a p53 negative regulating and controlling molecule and encode gene, which is characterized by the following: 1) SEQ ID of sequence table is No: 1; 2) the SEQ ID No.:1 amino acid residue sequence of sequence table is replaced, missed and added by one to ten amino acid residues to get the protein with inhibiting p53 transcription function; the transcription and inhibition of p53 negative regulating and controlling molecule is regulated and controlled negatively by ATM. The invention provides new target and idea for preventing leukemia and radiation disease.
Bibliography:Application Number: CN200510055660