Process for manufacturing wind-up type liver tissue engineering stent

• Main Authors: HE JIANKANG, LU BINGHENG, LIU YAXIONG, LI DICHEN
• Format: Patent
• Language: Chinese; English
• Published: 20.02.2008
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BANDAGES, DRESSINGS OR ABSORBENT PADS; BEER; BIOCHEMISTRY; CHEMISTRY; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DIAGNOSIS; ENZYMOLOGY; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PROSTHESES; SEPARATION; SPIRITS; SURGERY; TRANSPORTING; TREATMENT OR PROTECTION OF EYES OR EARS; VINEGAR; WINE

The invention discloses a method for producing the packed liver project bracket. First according to the inner micro-structure of natural liver, processing the bionic design of liver project bracket blood vessel system and the liver hole; using the fast molding micro-complex technique to produce the silicon rubber mould of bionic liver project bracket; plating the biological material with better bioavailability and biodegradability on the silicon rubber mould; packing the liver project bracket mould after removing mould to realize the spatial structure of liver project bracket; and wetting, sopping, cooling and drying the liver project bracket to attain the spatial liver project bracket with high porous property. When in the external culture, the endothelial cell of blood vessel is planted on the blood vessel network system, and the liver cell is planted on the liver cell hole; then, with the degradation of spatial liver project bracket, the endothelial cell can form the blood vessel, and the liver cell can in