Inhibidores de integrina alpha v beta 6 y alpha v beta 1 y sus usos

• Main Authors: JACOBSEN, John R, SHARMA, Lalit Kumar, FATHEREE, Paul Ross
• Format: Patent
• Language: Spanish
• Published: 15.03.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

En el presente documento se proporcionan inhibidores de la integrina alfa V beta 6 y alfa V beta 1, métodos para preparar dichos inhibidores de la integrina alfa V beta 6 y alfa V beta 1, composiciones farmacéuticas de inhibidores de la integrina alfa V beta 6 y alfa V beta 1, y métodos de tratamiento y/o prevención de diversos trastornos médicos en un sujeto mediante la administración de inhibidores de integrina alfa V beta 6 y alfa V beta 1 al sujeto que lo necesita. Provided herein are alpha V beta 6 and alpha V beta 1 integrin inhibitors, methods of making such alpha V beta 6 and alpha V beta 1 integrin inhibitors, pharmaceutical compositions of alpha V beta 6 and alpha V beta 1 integrin inhibitors, and methods of treating and/or preventing various medical disorders in a subject by administering to the subject in need thereof alpha V beta 6 and alpha V beta 1 integrin inhibitors. Provided herein are alpha V beta 6 and alpha V beta 1 integrin inhibitors, methods of making such alpha V beta 6 and alpha V beta 1 integrin inhibitors, pharmaceutical compositions of alpha V beta 6 and alpha V beta 1 integrin inhibitors, and methods of treating and/or preventing various medical disorders in a subject by administering to the subject in need thereof alpha V beta 6 and alpha V beta 1 integrin inhibitors.