Nuevo polisacárido y usos del mismo

NUEVO POLISACÁRIDO DE E. COLI Y USOS DEL MISMO Provided herein is an E. coli O polysaccharide, O25B. Also provided herein are prokaryotic host cells containing enzymes (e.g., glycosyltransferases) used in O25B production. The host cells provided herein produce O25B bioconjugates, wherein said biocon...

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Bibliographic Details
Main Authors MALLY, Manuela, KOWARIK, Michael T, HÄUPTLE, Micha A, WETTER, Michael L, KEMMLER, Stefan J, GAMBILLARA, Veronica
Format Patent
LanguageSpanish
Published 16.02.2018
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Summary:NUEVO POLISACÁRIDO DE E. COLI Y USOS DEL MISMO Provided herein is an E. coli O polysaccharide, O25B. Also provided herein are prokaryotic host cells containing enzymes (e.g., glycosyltransferases) used in O25B production. The host cells provided herein produce O25B bioconjugates, wherein said bioconjugates contain O25B linked to a carrier protein. Further provided herein are compositions, e.g., pharmaceutical compositions, including O25B and/or bioconjugates containing O25B. Such compositions can be used as vaccines against infection with ExPEC, and may further include one or more additional bioconjugates.
Bibliography:Application Number: CL20160002123