METODO PARA INHIBIR UNION DEL RECEPTOR DE MUERTE 6 (DR6) A LA PROTEINA PRECURSORA AMILOIDE (APP) QUE COMPRENDE UNO O MAS ANTAGONISTAS DEL DR6; USO DE DICHOS ANTAGONISTAS; METODO PARA IDENTIFICAR UNA MOLECULA DE INTERES QUE INHIBE LA UNION DEL DR6 A L

Methods and compositions comprising DR6 antagonists for use in treating neurological disorders, including Alzheimer's disease, are provided. The DR6 antagonists include anti-APP antibodies, anti-DR6 antibodies, DR6 immunoadhesins and DR6 variants (and fusion proteins thereof) which enhance grow...

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Bibliographic Details
Main Author NIKOLAEV, ANATOLY; TESSIER-LAVIGNE, MARC
Format Patent
LanguageSpanish
Published 25.07.2008
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Methods and compositions comprising DR6 antagonists for use in treating neurological disorders, including Alzheimer's disease, are provided. The DR6 antagonists include anti-APP antibodies, anti-DR6 antibodies, DR6 immunoadhesins and DR6 variants (and fusion proteins thereof) which enhance growth, regeneration or survival of mammalian neuronal cells or tissue.
Bibliography:Application Number: CL20070003793