COMPUESTOS DERIVADOS DE 5-OXO-5,8-DIHIDRO-PIRIDO-PIRIMIDINAS, INHIBIDORES C-FMS QUINASA; COMPOSICION FARMACEUTICA; Y USO PARA EL TRATAMIENTO DE ENFERMEDADES TALES COMO EPOC, ASMA, INFECCION POR VIH, PSORIASIS, DIABETES, OBESIDAD Y CANCER DE TUMORES S

The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a salt, stereoisomer, tautomer, crystalline, polymorph, amorphous, solvate, hydrate,...

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Bibliographic Details
Main Author PLAYER, MARK R.; PARSONS, WILLIAM H.; HUANG, HUI;HUTTA, DANIEL A.; HU, HUAPING; RINKER, JAMES
Format Patent
LanguageSpanish
Published 27.06.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a salt, stereoisomer, tautomer, crystalline, polymorph, amorphous, solvate, hydrate, ester, prodrug or metabolite form thereof, wherein A, Y, Z, R101 and R200 are described in the specification.
Bibliography:Application Number: CL20070003163