COMPUESTOS DERIVADOS DE AZABENZOTIOFENIL; COMPOSICION FARMACEUTICA; Y USO PARA LA INHIBICION DEL CRECIMIENTO CELULAR ANOMALO O DE TRATAMIENTO DE UN TRASTORNO HIPERPROLIFERATIVO

• Main Author: PRICE, STEPHEN; WILLIAMS, KAREN; SAVY, PASCAL PIERRE; DYKE, HAZEL JOAN; MONTANA, JOHN GARY; STANLEY, MARK S.; BAO, LIANG
• Format: Patent
• Language: Spanish
• Published: 14.03.2008
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to azabenzothiophenyl compounds of Formula I with anti-cancer and/or anti-inflammatory activity and more specifically to azabenzothiophenyl compounds which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or...