COMPUESTOS DERIVADOS 8B-VONIL-11B-(ALFA-SUSTITUIDOS)ALQUIL-ESTRA-1,3,5(10)-TRIENOS; COMPOSICIONES FARMACEUTICAS; COMPUESTOS INTERMEDIARIOS; USO PARA LA ANTICONCEPCION, PARA EL TRATAMIENTO DE CARCINOMAS DE OVARIO Y TUMORES DE CELULAS GRANULOSAS

This invention relates to 8beta-vinyl-11beta-(omega-substituted)alkyl-estra-1,3,5(10)-trienes of general formula I with ERbeta-antagonistic activity, process for their production, their intermediate products, pharmaceutical preparations that contain the compounds according to the invention, as well...

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Bibliographic Details
Main Author NICO BRAUER;OLAF PETERS;ALEXANDER HILLISCH;ROLF BOHLMANN; MARGIT RICHTER; HANS PETER MUHN
Format Patent
LanguageSpanish
Published 28.03.2005
Edition7
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Summary:This invention relates to 8beta-vinyl-11beta-(omega-substituted)alkyl-estra-1,3,5(10)-trienes of general formula I with ERbeta-antagonistic activity, process for their production, their intermediate products, pharmaceutical preparations that contain the compounds according to the invention, as well as their use for the production of pharmaceutical agents. The new compounds can be used for contraception in men and women without influencing other estrogen-sensitive organs such as the uterus or the liver. They are also suitable for treating benign or malignant proliferative diseases of the ovary, such as ovarian cancer and granulosa cell tumors.
Bibliography:Application Number: CL20040000856