CH671226

This invention relates to new 1-(hydroxystyryl)-5H-2,3-benzodiazepine derivatives of the general formula (I) and to a process for the preparation thereof, furthermore to pharmaceutical compositions containing the same, (I) wherein R stands for a hydrogen or halogen atom, or a C1-4 alkoxy group, R1 r...

Full description

Saved in:
Bibliographic Details
Main Authors HELTAI, KRISZTINA, ZOLYOMI, GABOR, SAROSSY, JUDITH (-KINCSESY), MORAVCSIK, IMRE, KUHAR, MARIA (-KUERTHY), ELEKES, ISTVAN, LANG, TIBOR, KOROESI, JENO, LANG, ZSUZSANNA (-RIHMER), POLGARI, ISTVAN, RABLOCZKY, GYOERGY, HAMORI, TAMAS
Format Patent
LanguageGerman
Published 15.08.1989
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:This invention relates to new 1-(hydroxystyryl)-5H-2,3-benzodiazepine derivatives of the general formula (I) and to a process for the preparation thereof, furthermore to pharmaceutical compositions containing the same, (I) wherein R stands for a hydrogen or halogen atom, or a C1-4 alkoxy group, R1 represents a hydrogen atom or a C1-4 alkyl group, R2 and R3 are identical and denote a C1-4 alkyl group, or combined they denote a methylene group. The compounds of the general formula (I) possess valuable positive inotropic (cardiotonic) potency, are capable to increase the myocardiac contractile force (heart performance in cardiac insufficiency), thus they can be applied in the therapy of chronic heart failure and coronary ailments.
Bibliography:Application Number: CH19870001916