ARZNEIMITTELPRAEPARATE MIT BLUTDRUCKSENKENDER WIRKUNG

• Main Authors: LASZLO NAGY, ENDRE KASZTREINER, EDIT KOSA, ERZSEBET SZUECS-CSASZAR, ZSUZSANNA HUSZTI, LASZLO TARDOS, GEZA SZILAGYI, JUDIT KOSARY, GABRIELLA KISS, JANOS BORVENDEG
• Format: Patent
• Language: German
• Published: 30.03.1984
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A pharmaceutical compositions with hypotensive effects which comprise a compound of formula (I) or a pharmaceutically acceptable acid addition salt thereof, (I) wherein R1 is formula (II) (II) wherein R4 and R5 each represent hydrogen, hydroxy, nitro at the same time R2 and R3 are hydrogen, or R1 are 3-chloro-6-pyridazinylamino, 3-methyl-6-pyridazinylamino or 3-carbamoyl-6-pyridazinylamino, and at the same time R2 and R3 form together formula (III), (III) wherein R6 is C1-4 alkyl group, R7 is hydrogen or a C1-4 alkyl group, and n is an integer of 1 to 3, or R2 and R3 form together a group of the general formula (IV), =Q-R8 (IV) wherein Q is C5-7 cycloaliphatic, and R8 is hydrogen, a C1-4 alkoxycarbonyl or a C2-4 alkyl, and a compound of formula (V) or a pharmaceutically acceptable acid addition salt thereof, (V) wherein R9 is naphthyl, 4-indolyl or 4-morpholino-1,2,5-thiadiazol-3-yl group or (VI) .