1-Phenoxy-2-hydroxy-3-tert.-butylamino propanes - beta-adrenolytics, hypotensives
(A) Cmpds. (I) R = CN or (3-6C) alkinyloxy (B) Salts of (I). beta-Adrenolytics and hypotensives. Dose 1-300 mg. (p.o.), 0.1-25 mg. (parent). (a) + Me3CNHCONHCMe3 Z = or -CHOHCH2Hal. (b) + HalCMe (c) (III) + H2NCMe3 (d) By deprotection of an O- or N-protected deriv. of (I), e.g. an O- or N-acyl or be...
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Main Authors | , , |
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Format | Patent |
Language | English German |
Published |
31.07.1971
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Edition | 1 |
Subjects | |
Online Access | Get full text |
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Summary: | (A) Cmpds. (I) R = CN or (3-6C) alkinyloxy (B) Salts of (I). beta-Adrenolytics and hypotensives. Dose 1-300 mg. (p.o.), 0.1-25 mg. (parent). (a) + Me3CNHCONHCMe3 Z = or -CHOHCH2Hal. (b) + HalCMe (c) (III) + H2NCMe3 (d) By deprotection of an O- or N-protected deriv. of (I), e.g. an O- or N-acyl or benzyl deriv. (e) (f) (g) (I) (R=NH2) (I) (R=CN). |
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Bibliography: | Application Number: CH19700011680 |