Verfahren zur Herstellung von N-Carbamoyl-hydrazinoessigsäureestern

<FORM:1121312/C2/1> <FORM:1121312/C2/2> 1 - (5 - Nitrofurfurylidene - amino) - hydantoins (some of which are novel) having the Formula (I), in which R is C1- 8 alkyl, C2- 6 alkenyl, C1- 6 alkoxy-carbonyl, C5- 8 cycloalkyl, phenyl, phenyl carrying one or two C1- 6 alkyl substituents or ph...

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Bibliographic Details
Main Authors SIMON HOFMAN,PETRUS, STELT,CORNELIS,VAN DER
Format Patent
LanguageGerman
Published 15.04.1968
Edition1
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:<FORM:1121312/C2/1> <FORM:1121312/C2/2> 1 - (5 - Nitrofurfurylidene - amino) - hydantoins (some of which are novel) having the Formula (I), in which R is C1- 8 alkyl, C2- 6 alkenyl, C1- 6 alkoxy-carbonyl, C5- 8 cycloalkyl, phenyl, phenyl carrying one or two C1- 6 alkyl substituents or phenyl-C1- 6 alkyl, are prepared by effecting ring closure of a compound of Formula (II), in which R1 is a hydrocarbon group, by treatment with a strong mineral acid. The novel hydantoins are those in which R is C1- 4 alkyl or cyclohexyl. Pharmaceutical compositions having anti-bacterial and, when R is butyl, fungistatic properties, for oral administration, comprise a compound of Formula (I) with a carrier.
Bibliography:Application Number: CH19660000941