Procédé de fabrication du dérivé monoaminoguanidine d'adrénochrome

The invention comprises adrenochrome monoaminoguanidine and salts thereof with hydrohalic acids, monocarboxylic and sulphonic acids. The compound is prepared by mixing an aqueous solution of adrenochrome with a salt of aminoguanidine, e.g. the nitrate, together with a sufficient amount of a mineral...

Full description

Saved in:
Bibliographic Details
Main Author YAMANISHI,YASUHITO
Format Patent
LanguageFrench
Published 31.03.1966
Edition1
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:The invention comprises adrenochrome monoaminoguanidine and salts thereof with hydrohalic acids, monocarboxylic and sulphonic acids. The compound is prepared by mixing an aqueous solution of adrenochrome with a salt of aminoguanidine, e.g. the nitrate, together with a sufficient amount of a mineral acid to catalyse the reaction, and rendering the solution alkaline with ammonia or caustic soda to precipitate an orange-coloured product. The compound may be refined by dissolving in aqueous acetic acid and precipitating with caustic soda. Adrenochrome monoaminoguanidine and its salts have homostatic and capillary-stabilizing actions and are used in aqueous solutions as injections.
Bibliography:Application Number: CH19630006455